Monitoring of the Immune Response of Pregnant Ewes and their Offsprings Following the Vaccination of the Dams with Peste Des Petits Ruminants Attenuated Vaccine (75/1)

Document Type : Original Article

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Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo

Abstract

Assessment of the neutralizing antibody response to the attenuated strain of peste des petits ruminants Nigerian strain (75/1) in 5 pregnant ewes revealed a geometric mean titre of 194, four weeks post Vaccination. Such an appreciably high titre was found to be dropped to 73.5, throughout 48 hours post parturn. Suckling kids born to these dams passively acquired a titre of 84.5 throughout their first month of life that dropped to 48.5 at the age of 2 months. At their 5th month of age their immune titre was found to be only 4. Data generated from this study might be
of value in launching vaccination campaigns against peste des petits ruminants disease. 

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Journal of Veterinary Medical Research
Volume 22, Issue 1
March 2013
Pages 160-163

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