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M. M. A, K., G. A., R., M. Z., F., U., H., M. Safwat, N. (2020). Radiologic, Ultrasonic and pathological assessments of locally applied Chitosan on promotion of experimentally induced tibial fracture healing in rats. Journal of Veterinary Medical Research, 27(1), 23-36. doi: 10.21608/jvmr.2020.69691
Kotb, M. M. A; Ragab, G. A.; Fathy, M. Z.; Haggag, U.; Nesreen M. Safwat. "Radiologic, Ultrasonic and pathological assessments of locally applied Chitosan on promotion of experimentally induced tibial fracture healing in rats". Journal of Veterinary Medical Research, 27, 1, 2020, 23-36. doi: 10.21608/jvmr.2020.69691
M. M. A, K., G. A., R., M. Z., F., U., H., M. Safwat, N. (2020). 'Radiologic, Ultrasonic and pathological assessments of locally applied Chitosan on promotion of experimentally induced tibial fracture healing in rats', Journal of Veterinary Medical Research, 27(1), pp. 23-36. doi: 10.21608/jvmr.2020.69691
M. M. A, K., G. A., R., M. Z., F., U., H., M. Safwat, N. Radiologic, Ultrasonic and pathological assessments of locally applied Chitosan on promotion of experimentally induced tibial fracture healing in rats. Journal of Veterinary Medical Research, 2020; 27(1): 23-36. doi: 10.21608/jvmr.2020.69691

Radiologic, Ultrasonic and pathological assessments of locally applied Chitosan on promotion of experimentally induced tibial fracture healing in rats

Article 4, Volume 27, Issue 1, Spring 2020, Page 23-36  XML PDF (1.61 MB)
Document Type: Original Article
DOI: 10.21608/jvmr.2020.69691
Authors
Kotb, M. M. A1; Ragab, G. A.2; Fathy, M. Z.2; Haggag, U.2; Nesreen M. Safwat3
1Veterinarian in Garado Veterinary Unit, El- Fayoum, Egypt.
2Surgery, Anesthesiology and Radiology Department, Faculty of Veterinary Medicine, Beni-Suef Univ., Beni Suef, Egypt.
3Pathology Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni Suef, Egypt.
Abstract
The objective of the present study was to evaluate the ability of Chitosan to promote induced tibial fracture healing in a rat model. The study was conducted on 14 albino rats divided into two equal groups (seven rats in each group). The first group was considered as a control group. The second group was injected Chitosan solution 0.1 mg/kg into the fracture gap. The progress of healing in each group was evaluated by clinical, radiography, ultrasonography and pathological examinations. The healing process was observed to be superior in the Chitosan group compared to the control one. Chitosan was found to promote healing of injured bone and is suggested to be used in cases of complicated or delayed bone fracture.
 
Keywords
albino rats; fracture; Healing; pathological; Radiological; Ultrasonic
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