Comparison of tramadol, lidocaine and tramadol-lidocaine combination for epidural analgesia in goats

Document Type : Original Article


Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt.


The aim of this study was to compare the analgesic effect of tramadol,
lidocaine and tramadol-lidocaine combination injected in the epidural space
in goats. Nine goats were used to compare the epidural analgesic effect of
tramadol (3 mg / kg), 2% lidocaine (2.86 mg/kg) and tramadol-lidocaine
combination (1 mg /kg and 2.46 mg kg, resp.). Onset time, duration, and
degree of analgesia and ataxia were recorded as well as Heart rate (HR),
respiratory rate (RR), rectal temperature (RT), and biochemical parameters
were recorded. Time to onset and duration of analgesia, were tramadol 10
min and 225 min; lidocaine 4 min and 85 min and tramadol-lidocaine 4 min
and 130 min respectively. Onset time and duration were significantly longer
with tramadol and tramadol-lidocaine combination than the other
treatment. Ataxia was not observed in tramadol and mildly observed in
tramadol-lidocaine combination and was severing in lidocaine. Tramadol
and tramadol-lidocaine combination might be clinically useful to provide
analgesia in goats for long-duration surgical procedures than lidocaine


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