Immunomodulating and zootechnical effect of some bacterial components on broiler chicken vaccinated with Newcastle disease vaccine

Document Type : Original Article


1 Department of Poultry Diseases

2 Department of Virology, Faculty of Veterinary Medicine, Beni-Suef University


This study was carried out to evaluate the immunomodulating effects of, inactivated cells of Propionibacterium acnes and cell wall lipopolysaccharide (LPS) of the a pathogenic E. coli (INMUNAIR® 17.5) 0.5ml/ L and 1-3, 1-6 β-glucans (BETAPOLO®) 1 ml / L on the immune response of chickens to Newcastle disease (ND) vaccine. The results showed that administration of IMR before vaccination was resulted in food conversion rate (FCR) higher than after vaccination . Significantly higher NDV HI antibody titers in IMR and Betapolo medicated groups as compared with control groups which in turn induce high protection rate in challenge test .Thymus, spleen and bursal indices of control negative showed significantly lower values than vaccinated medicated and non- vaccinatedmedicated groups (P≤ 0.05).


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