Pathogenicity of Escherichia coli O125 in commercial broiler chickens

Document Type : Original Article


1 Faculty of agriculture , El Minya University

2 Poultry Diseases, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt. 3

3 Poultry Diseases , Faculty of Veterinary Medicine , Cairo University ,Giza12618, Egypt

4 Poultry Diseases, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt.

5 Bacteriology, Mycology and Immunology Disease, Faculty of Veterinary Medicine, Beni-Suef University


Commercial broiler chickens are frequently infected with Ecoli serotypes in form of collibacillosis which
characterized as an initial respiratory infection (air sacculitis) followed by generalized septicemia, perihepatitis and
pericarditis. The present work aimed to study the ability of E.coli O125 previuosly isolated and identified from
diseased broilers suffered from pericarditis , airsacculitis and perihapatitis to induce a disease and The current study
aimed to determine the pathogenicity of E. coli serogroup O125 in broiler chicks, a trial of prevention and treatment
using probiotic ( Guardyazin-m) or antibiotic (Cipronate20%). The chicks were divided into seven groups including
control negative, orally infected , subcutenously infected , probiotic treated group, and finally antibiotic treated
group. The clinical signs, mortality, performance parameters and postmortem examination as well as the
pathological changes in liver and intestine were recorded. The probiotic group gave the best results in controlling
infection by E. coli O125 followed by antibiotic. In conclusion, the E. coli O125 serogroup was pathogenic to chicks
when experimentally inoculated, so particular attention must be directed toward E. coli O125 as a pathogen infecting
bird. Also probiotics was of great value in protection against the E. coli infection and improve the performance
parameters of chicks . Its effect on feed consumption , weekly body weight gain and feed conversion rate (FCR) was


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